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词汇 quinacrine
释义

Definition of quinacrine in English:

quinacrine

noun ˈkwɪnəkrɪnˈkwɪnəkriːnˈkwinəˌkrin
mass nounMedicine
  • 1A synthetic compound derived from acridine, used as an anthelmintic and antimalarial drug.

    〔医〕奎纳克林,阿的平

    Example sentencesExamples
    • The drugs are quinacrine, used to treat malaria and the tropical parasite infection giardiasis, and chlorpromazine, which is given to patients with schizophrenia and other psychotic conditions.
    • The Medical Research Council, which will oversee the trials, said national guidelines for studies of the antimalarial drug quinacrine will probably be agreed next month.
    • Hydroxychloroquine is the most widely used; its effectiveness was studied in combination with quinacrine, another antimalarial drug.
    • If standard therapeutic regimens fail because of immunodeficiency or other issues, combinations of metronidazole and quinacrine can be administered for three weeks.
    1. 1.1Biochemistry A nitrogen mustard derived from quinacrine, used as a fluorescent stain for chromosomes.
      〔生化〕芥奎吖因
      Example sentencesExamples
      • First, cytogenetic techniques, especially quinacrine staining, were developed, enabling each chromosome to be recognized by its unique banding pattern.

Origin

1930s: blend of quinine and acridine.

Definition of quinacrine in US English:

quinacrine

nounˈkwinəˌkrin
Medicine
  • 1A synthetic compound derived from acridine, used as an anthelmintic and antimalarial drug.

    〔医〕奎纳克林,阿的平

    Example sentencesExamples
    • The drugs are quinacrine, used to treat malaria and the tropical parasite infection giardiasis, and chlorpromazine, which is given to patients with schizophrenia and other psychotic conditions.
    • If standard therapeutic regimens fail because of immunodeficiency or other issues, combinations of metronidazole and quinacrine can be administered for three weeks.
    • Hydroxychloroquine is the most widely used; its effectiveness was studied in combination with quinacrine, another antimalarial drug.
    • The Medical Research Council, which will oversee the trials, said national guidelines for studies of the antimalarial drug quinacrine will probably be agreed next month.
    1. 1.1Biochemistry A nitrogen mustard derived from this, used as a fluorescent stain for chromosomes.
      〔生化〕芥奎吖因
      Example sentencesExamples
      • First, cytogenetic techniques, especially quinacrine staining, were developed, enabling each chromosome to be recognized by its unique banding pattern.

Origin

1930s: blend of quinine and acridine.

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