Definition of lamellipodium in English:

lamellipodium

nounPlural lamellipodia ləˌmɛlɪˈpəʊdɪəmləˌmeləˈpōdēəm

Zoology

A flattened extension of a cell, by which it moves over or adheres to a surface.
〔动〕片状伪足
Example sentencesExamples
- Many models are based on the fact that the actin polymerization is a major contributor to the protrusive force, which leads to the extension of the lamellipodia of crawling cells on a hard substrate.
- In cells without a lamellipodium, the lamella reached all the way to the leading edge and the pattern of turnover did not deviate from its randomness, even in phases of pronounced protrusion.
- Polymerization is thought to generate protrusive forces that push forth a lamellipodium and begin the cell motility cycle.
- In these motile cells, lamellipodia of various shape are continually extended in different directions.
- More specifically, an increase in thermal fluctuations of actin filaments in the softer cells and the lamellipodium can expedite the intercalation of G-actin that leads to the enhanced protrusion.

Derivatives

lamellipodial

adjective

Zoology

Actin, the major component of the lamellipodial cytoskeleton, exists in monomeric (G-actin) and rod-like polymerized filament (F-actin) forms.
Example sentencesExamples
- Kymographic analysis of EGF-stimulated lamellipodial dynamics revealed that the temporal stability of lamellipodial protrusions similarly increased with fibronectin concentration.
- Third, as far as the diffusion-limited growth is concerned, our estimates were made for the steadily protruding lamellipodial leading edge.
- Interestingly, that the stability of lamellipodial protrusion events also increases upon addition of EGF indirectly supports the idea that EGF actually increases adhesion at the front of cells.
- Another possible role of relatively rigid actin bundles embedded into the lamellipodial actin sheet is to strengthen the lamellipodium against buckling, by analogy with engineered macroscopic structures.

Origin

1970s: from lamella, on the pattern of pseudopodium.

Definition of lamellipodium in US English:

lamellipodium

nounləˌmeləˈpōdēəm

Zoology

A flattened extension of a cell, by which it moves over or adheres to a surface.
〔动〕片状伪足
Example sentencesExamples
- In cells without a lamellipodium, the lamella reached all the way to the leading edge and the pattern of turnover did not deviate from its randomness, even in phases of pronounced protrusion.
- In these motile cells, lamellipodia of various shape are continually extended in different directions.
- Many models are based on the fact that the actin polymerization is a major contributor to the protrusive force, which leads to the extension of the lamellipodia of crawling cells on a hard substrate.
- More specifically, an increase in thermal fluctuations of actin filaments in the softer cells and the lamellipodium can expedite the intercalation of G-actin that leads to the enhanced protrusion.
- Polymerization is thought to generate protrusive forces that push forth a lamellipodium and begin the cell motility cycle.

Origin

1970s: from lamella, on the pattern of pseudopodium.

词汇	lamellipodium
释义	Definition of lamellipodium in English: lamellipodium nounPlural lamellipodia ləˌmɛlɪˈpəʊdɪəmləˌmeləˈpōdēəm Zoology A flattened extension of a cell, by which it moves over or adheres to a surface. 〔动〕片状伪足 Example sentencesExamples Many models are based on the fact that the actin polymerization is a major contributor to the protrusive force, which leads to the extension of the lamellipodia of crawling cells on a hard substrate. In cells without a lamellipodium, the lamella reached all the way to the leading edge and the pattern of turnover did not deviate from its randomness, even in phases of pronounced protrusion. Polymerization is thought to generate protrusive forces that push forth a lamellipodium and begin the cell motility cycle. In these motile cells, lamellipodia of various shape are continually extended in different directions. More specifically, an increase in thermal fluctuations of actin filaments in the softer cells and the lamellipodium can expedite the intercalation of G-actin that leads to the enhanced protrusion. Derivatives lamellipodial adjective Zoology Actin, the major component of the lamellipodial cytoskeleton, exists in monomeric (G-actin) and rod-like polymerized filament (F-actin) forms. Example sentencesExamples Kymographic analysis of EGF-stimulated lamellipodial dynamics revealed that the temporal stability of lamellipodial protrusions similarly increased with fibronectin concentration. Third, as far as the diffusion-limited growth is concerned, our estimates were made for the steadily protruding lamellipodial leading edge. Interestingly, that the stability of lamellipodial protrusion events also increases upon addition of EGF indirectly supports the idea that EGF actually increases adhesion at the front of cells. Another possible role of relatively rigid actin bundles embedded into the lamellipodial actin sheet is to strengthen the lamellipodium against buckling, by analogy with engineered macroscopic structures. Origin 1970s: from lamella, on the pattern of pseudopodium. Definition of lamellipodium in US English: lamellipodium nounləˌmeləˈpōdēəm Zoology A flattened extension of a cell, by which it moves over or adheres to a surface. 〔动〕片状伪足 Example sentencesExamples In cells without a lamellipodium, the lamella reached all the way to the leading edge and the pattern of turnover did not deviate from its randomness, even in phases of pronounced protrusion. In these motile cells, lamellipodia of various shape are continually extended in different directions. Many models are based on the fact that the actin polymerization is a major contributor to the protrusive force, which leads to the extension of the lamellipodia of crawling cells on a hard substrate. More specifically, an increase in thermal fluctuations of actin filaments in the softer cells and the lamellipodium can expedite the intercalation of G-actin that leads to the enhanced protrusion. Polymerization is thought to generate protrusive forces that push forth a lamellipodium and begin the cell motility cycle. Origin 1970s: from lamella, on the pattern of pseudopodium.
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