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词汇 nonsense mutation
释义

Definition of nonsense mutation in English:

nonsense mutation

noun
Genetics
  • A mutation in which a sense codon that corresponds to one of the twenty amino acids specified by the genetic code is changed to a chain-terminating codon.

    〔遗传〕无义突变

    Example sentencesExamples
    • The first spans codons 195-196 and induces a silent substitution at codon 195 and a nonsense mutation at codon 196.
    • The proximity of the nonsense mutation to the start codon indicates that these mutations are null alleles.
    • Another nonsense mutation at codon 187 is shared by the human, the chimpanzee and the gorilla, so that it is most likely to have occurred in their ancestral species.
    • A nonsense mutation is represented by a solid red circle.
    • Another mutant isolated from the screen, LPY727, contained a nonsense mutation at amino acid 15.

Definition of nonsense mutation in US English:

nonsense mutation

noun
Genetics
  • A mutation in which a sense codon that corresponds to one of the twenty amino acids specified by the genetic code is changed to a chain-terminating codon.

    〔遗传〕无义突变

    Example sentencesExamples
    • The first spans codons 195-196 and induces a silent substitution at codon 195 and a nonsense mutation at codon 196.
    • Another mutant isolated from the screen, LPY727, contained a nonsense mutation at amino acid 15.
    • A nonsense mutation is represented by a solid red circle.
    • The proximity of the nonsense mutation to the start codon indicates that these mutations are null alleles.
    • Another nonsense mutation at codon 187 is shared by the human, the chimpanzee and the gorilla, so that it is most likely to have occurred in their ancestral species.
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