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词汇 pseudouridine
释义

Definition of pseudouridine in English:

pseudouridine

nounˌsjuːdəʊˈjʊərɪdiːnˌso͞odōˈyo͝orədēn
mass nounBiochemistry
  • A nucleoside present in transfer RNA and differing from uridine in having the sugar residue attached at a carbon atom instead of nitrogen.

    〔生化〕假尿(嘧啶核)苷

    Example sentencesExamples
    • PSEUDOURIDINE has occurred in all hitherto analysed biological systems as a component of soluble ribonucleic acid.
    • A marker of protein breakdown, urinary pseudouridine, was higher in the patients than in the healthy subjects: 25.1 versus 14.0 mmol per mmol creatinine.
    • We assessed the clearance of endogenous pseudouridine in humans to evaluate the potential use of this modified nucleoside as a marker of glomerular filtration rate.
    • Excretion of pseudouridine (5-ribosyluracil, PSU), a modified nucleoside indicator of RNA and hence of cellular protein breakdown, is increased in disease states associated with chronic systemic inflammation.

Definition of pseudouridine in US English:

pseudouridine

nounˌso͞odōˈyo͝orədēn
Biochemistry
  • A nucleoside present in transfer RNA and differing from uridine in having the sugar residue attached at a carbon atom instead of nitrogen.

    〔生化〕假尿(嘧啶核)苷

    Example sentencesExamples
    • PSEUDOURIDINE has occurred in all hitherto analysed biological systems as a component of soluble ribonucleic acid.
    • Excretion of pseudouridine (5-ribosyluracil, PSU), a modified nucleoside indicator of RNA and hence of cellular protein breakdown, is increased in disease states associated with chronic systemic inflammation.
    • We assessed the clearance of endogenous pseudouridine in humans to evaluate the potential use of this modified nucleoside as a marker of glomerular filtration rate.
    • A marker of protein breakdown, urinary pseudouridine, was higher in the patients than in the healthy subjects: 25.1 versus 14.0 mmol per mmol creatinine.
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